Priapismo y leucemia mieloide crónica en adolescente. Debut poco frecuente. Reporte de caso / Priapism and chronic myeloid leukemia in an adolescent. Rare debut presentation. A case report

El priapismo es una erección dolorosa y persistente acompañada o no de estímulo sexual. Una causa poco frecuente de esta anormalidad es la leucemia mieloide crónica. Se han reportado pocos casos de priapismo como manifestación inicial de una leucemia de este tipo en pacientes adolescentes. A continuación, se informa el caso de un paciente de 16 años de edad que presentó priapismo como manifestación inicial de una leucemia mieloide crónica. Durante su evolución, no se realizó aspiración de los cuerpos cavernosos. Se inició tratamiento hematológico específico y, ante la persistencia del priapismo, fue necesario realizar un shunt de cuerpos cavernosos en dos ocasiones, tratamiento a pesar del cual existen altas probabilidades de secuelas.

Priapism is a painful and persistent erection, with or without sexual stimulation. A rare cause of such abnormality is chronic myeloid leukemia. Few cases of priapism as an initial manifestation of this type of leukemia have been reported in adolescent patients. Here we describe the case of a 16-year-old patient who presented with priapism as the initial manifestation of chronic myeloid leukemia. No cavernosal aspiration was performed. A specific hematological treatment was started and, given the persistence of priapism, the patient required 2 corpora cavernosa shunt procedures; despite this treatment, there is a high probability of sequelae.

Priapismo: abordaje clínico y manejo de urgencia / Priapism: clinical approach and emergency management

Priapism is a persistent erection, often painful, lasting more than 4 hours and unrelated to sexual stimulation. Based on clinical and pathophysiological features, priapism can be classified as ischemic, nonischemic and stuttering. Ischemic priapism is the most frequent form and represents a urological emergency. Although it is described as a low frequency entity, its timely diagnosis and immediate intervention are essential in the reestablishment of cavernous blood flow and in the prevention of necrosis and permanent erectile dysfunction. Intracavernous blood aspiration and injection of a-adrenergic agents correspond to the first-line options for the management of cases of ischemic priapism. Surgical shunts continue to be the most widely used surgical option for the management of prolonged ischemic priapism refractory to non-invasive management, with emerging evidence supporting the early implantation of a penile prosthesis. The objective of this review article is to describe the keys to the clinical approach and acute management of priapism in the emergency department. (AU)

Prevalence of priapism in individuals with sickle cell disease and implications on male sexual function / Prevalência de priapismo em indivíduos com doença falciforme e suas implicações na função sexual masculina

ABSTRACT Objective To evaluate epidemiological aspects of priapism in patients with sickle cell disease, and these aspects impact on adult sexual function. Methods This was a cross-sectional study including individuals with sickle cell disease who were evaluated at a reference center for sickle cell. Participants completed a structured questionnaire about their sociodemographic characteristics and priapism events. Sexual function was assessed using validated two instruments, the Erection Hardness Score and one about the sex life satisfaction. Results Sixty-four individuals with median aged of 12 (7 to 28) years were interviewed. The prevalence of priapism was 35.9% (23/64). The earliest priapism episode occurred at 2 years of age and the latest at 42 years. The statistical projection was that 71.1% of individuals of the study would have at least one episode of priapism throughout life. Patients with episodes of priapism (10/23) had significantly worse erectile function Erection Hardness Score of 2 [1-3]; p=0.01 and were less satisfied with sexual life 3 [3-5]; p=0.02. Conclusion Priapism is usually present in childhood, and severe episodes are associated with cavernous damage, impairment in the quality of the erection, and lower sexual satisfaction.

RESUMO Objetivo Avaliar aspectos epidemiológicos do priapismo em pacientes com doença falciforme e o impacto desses aspectos na função sexual de adultos. Métodos Trata-se de estudo transversal, que incluiu indivíduos com doença falciforme acompanhados em um centro de referência. Os participantes responderam a um questionário estruturado acerca das características sociodemográficas e eventos de priapismo. A função sexual foi avaliada por meio de dois instrumentos validados, a Escala de Rigidez de Ereção e um sobre satisfação com a vida sexual. Resultados Foram entrevistados 64 indivíduos com média de idade de 12 (7-28) anos. A prevalência de priapismo foi de 35,9% (23/64). O episódio mais precoce ocorreu aos 2 anos de idade e o mais tardio, aos 42 anos. A projeção estatística foi de que 71,1% desses sujeitos teriam pelo menos um episódio de priapismo ao longo da vida. Pacientes adultos com episódios de priapismo (10/23) apresentaram função erétil significativamente pior Escala de Rigidez de Ereção de 2 [1-3]; p=0,01 e estavam menos satisfeitos com a vida sexual 3 [3-5]; p=0,02. Conclusão O priapismo manifesta-se desde a infância, e episódios graves estão associados a dano cavernoso, prejuízo na qualidade da ereção e menor satisfação sexual.

Prognostic factors and outcome of management of ischemic priapism in Zaria, Nigeria

Objectives: The objective of this study was to determine the nuances of management, prognostic factors, and outcome of ischemic priapism in patients seen at Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. Patients and Methods: We retrospectively studied the case notes of all patients managed for ischemic priapism in the Ahmadu Bello University Teaching Hospital, Zaria, over a period of 10 years (2006­2015). The data extracted included patients' age, occupation, duration of painful penile erection, and previous episodes. Addition information including precipitating factors, hemoglobin genotype, treatment, and complications was also retrieved. Data obtained were analyzed using SPSS version 20. Results: The records of a total of forty patients managed for priapism over the period under review were retrieved. Thirty-three (82.5%) of these patients had an operative intervention. The mean age was 23.7 years with a range of 8­53 years. Sixty percent of patients were young adults in their third decade of life. The minimum duration of erection at presentation was 18 h and a maximum period of 10 days with a mean of 105.5 h (4 days). Thirty-three patients (82.5%) had sickle cell anemia (HbSS). Erectile dysfunction (ED) accounted for 60% of all forms of postpriapism complications. Five patients (12.5%) had residual tumescence from fibrosis, and three patients had recurrence outside the immediate postoperative period. Duration of symptoms before surgical intervention, SSA and previous episodes were the most important prognostic factors. Conclusion: Priapism is a disease of the young, mostly sickle cell anemic patients. Late presentation remains the norm in our environment, hence a higher incidence of ED. The distal penile shunt is an effective means of achieving detumescence even with failed conservative management. Favorable outcome is highly dependent on the duration of erection and early intervention

Recurring priapism may be a symptom of voiding dysfunction – case report and literature review

ABSTRACT Recurring priapism is rare in pre-pubertal children and may be attributed to multiple causes. We propose that voiding dysfunction (VD) may also justify this symptom and detail a clinical case of recurring stuttering priapism associated to overactive bladder that completely resolved after usage of anticholinergics and urotherapy. Sacral parasympathetic activity is responsible for detrusor contraction and for spontaneous erections and a relationship between erections and bladder status has been proved in healthy subjects (morning erections) and models of medullar trauma. High bladder pressures and/or volumes, voiding incoordination and posterior urethritis can potentially trigger reflex erections.

Does platelet activity play a role in the pathogenesis of idiopathic ischemic priapism?

ABSTRACT Purpose Mean platelet volume (MPV) is used to measure platelet size and is defined as a potential marker of platelet reactivity. Higher MPV levels have been defined as a risk factor for increased incidence of intravascular thrombosis and its associated diseases. We aimed to determine whether a relationship exists between the MPV and veno-occlusive component of idiopathic ischemic priapism (IIP). Materials and methods Between 2010 and 2014, 38 subjects were analyzed in two groups. One was composed of 15 patients with diagnosis as IIP in our institute, and the other contained 23 healthy control subjects. Complete blood count reports were retrospectively evaluated in both groups. MPV, platelet count (PLT), platelet distribution width (PDW), white blood cells (WBC), red blood cells (RBC), hemoglobin (Hb), reticulocyte distribution width (RDW) were measured in both groups. : Results The mean ages were similar in IIP patients (45.86±15.82) and control subjects (47.65±10.99). The mean MPV values of IIP patients were significantly higher than control subjects (p<0.05). In contrast, also PLT counts were significantly lower in IIP patients, compared to control subjects (p<0.05). The mean hemoglobin and WBC values were significantly lower in control group (p<0.05). There was no significant difference of RBC, PDW and RDW values in both groups. Conclusions We found that the MPV was significantly higher in IIP patients compared to control subjects. The high MPV levels may have contributed to the veno-occlusive etiopathogenesis of IIP disease. We strongly suggest further prospective studies to recommend the use of MPV in routine practice.

Ischemic Priapism in South-East Nigeria: Presentation; Management Challenges; and Aftermath Issues

Context: Ischemic priapism is the more common variety of priapism and often presents late. Outcome is largely dependent on the duration of ischemia. Aims: To determine the etiology; presentation; management; and outcome of ischemic priapism. Settings and Design: Retrospective analysis of consecutive cases presenting to three hospitals offering specialist urological services in South-East Nigeria from January 2000 to December 2010. Patients and Methods: Fifteen patients were assessed for clinical data and outcome. Statistical Analysis Used: The data were analyzed descriptively and inferentially using Statistical Package for Social Sciences (SPSS version 16; SPSS Inc.; Chicago IL; USA) with P 0.05. Results: Mean age was 30.5 years (standard deviation [SD]

Priapismo de alto flujo postraumático en paciente pediátrico tratado con embolización arterial selectiva / Postraumatic high-flow priapism in pediatric patient treated with selective arterial embolization

El priapismo arterial es una rara patología en pacientes pediátricos, originada por una fístula entre la arteria cavernosa y los sinusoides del cuerpo cavernoso, habitualmente secundaria a un traumatismo perineal. Presentamos el caso de un varón de 16 años con priapismo arterial de 5 días de evolución tras una caída a horcajadas, tratado satisfactoriamente mediante embolización arterial supraselectiva con material reabsorbible. Seis meses después, el paciente presenta detumescencia completa sin disfunción eréctil asociada. La embolización arterial en pacientes pediátricos es compleja debido al menor calibre arterial y la necesidad de control de la arteria pudenda interna contralateral para evitar el desarrollo de complicaciones. La utilización de material reabsorbible permite disminuir el riesgo de disfunción eréctil posterior y, aunque presenta un mayor índice de recurrencias, constituye una alternativa eficaz en el tratamiento de esta patología.

Arterial priapism is a rare condition in pediatric patients, caused by a fistula between the cavernous artery and the sinusoids of the corpus cavernosum, usually secondary to perineal trauma. We report the case of a 16 year old child with arterial priapism of 5 days duration following a fall astride, successfully treated by superselective arterial embolization with absorbable material. Six months later the patient had complete detumescence without secondary erectile dysfunction. Arterial embolization in pediatric patients is complex due to the smaller arterial size and the need to control the contralateral internal pudendal artery to prevent the development of complications. The use of absorbable material helps reduce the risk of subsequent erectile dysfunction and, although it has a higher rate of recurrence, is an alternative for the treatment of this pathology.

Partial Priapism Treated with Pentoxifylline

ABSTRACTMain findings:A 26-year-old man suffering from partial priapism was successfully treated with a regimen including pentoxifylline, a nonspecific phosphodiesterase inhibitor that is often used to conservatively treat Peyronie's disease.Case hypothesis:Partial priapism is an extremely rare urological condition that is characterized by thrombosis within the proximal segment of a single corpus cavernosum. There have only been 36 reported cases to date. Although several factors have been associated with this unusual disorder, such as trauma or bicycle riding, the etiology is still not completely understood. Treatment is usually conservative and consists of a non-steroidal anti-inflammatory and anti-thrombotic.Promising future implications:This case report supports the utilization of pentoxifylline in patients with partial priapism due to its anti-fibrogenic and anti-thrombotic properties.

Anestesia y priapismo / Anesthesia and priapism

Priapismo se define como la erección persistente del pene que no está asociado con la estimulación o deseo sexual. Su ocurrencia en el intraoperatorio durante anestesia general o neuroaxial (espinal, epidural) es poco frecuente, sin embargo, éste puede provocar complicaciones, como sangrado excesivo o trauma uretral, demoras, e incluso la cancelación del procedimiento quirúrgico. La literatura existente con respecto a este tema es escasa y en muchos casos contradictoria, sobre todo cuando se trata de definir la técnica anestésica (general o neuroaxial) responsable o capaz de resolver el caso. En la siguiente revisión analizaremos los agente farmacológicos y no farmacológicos, junto con las técnicas anestésicas capaces de producir y resolver el priapismo intraoperatorio.

Priapism is defined as a persistent penile erection that is not associated with stimulation or sexual desire. Its occurrence during general or neuraxial anesthesia (spinal, epidural) is rare, however, it can cause complications such as excessive bleeding or urethral trauma, delays and even cancellation of the surgical procedure. The literature on this subject is scarce and contradictory in many cases, especially when it comes to defining the anesthetic technique (general or neuraxial) responsible or able to resolve the case. The following review will discuss the pharmacological and non-pharmacological agents, along with anesthetic techniques capable of producing and resolve intraoperative priapism.

Homozygous sickle cell disease in Uganda and Jamaica a comparison of Bantu and Benin haplotypes / La anemia de células falciformes homocigóticas en Uganda y Jamaica comparación de haplotipos Bantú y Benin

OBJECTIVE: To compare the haematological and clinical features of homozygous sickle cell (SS) disease in Bantu and Benin haplotypes in a cross-sectional study of 115 Ugandan patients attending the Sickle Cell Clinic at Mulago Hospital, Kampala, Uganda, with 311 patients in the Jamaican Cohort Study. METHODS: This involved comparison of clinical features and haematology with special reference to genetic determinants of severity including fetal haemoglobin levels, beta-globin haplotype and alpha thalassaemia status. RESULTS: The Bantu haplotype accounted for 94% of HbS chromosomes in Ugandan patients and the Benin haplotype for 76% of HbS chromosomes in Jamaica. Ugandan patients were marginally more likely to have alpha thalassaemia, had similar total haemoglobin and fetal haemoglobin levels but had higher reticulocyte counts and total bilirubin levels consistent with greater haemolysis. Ugandan patients had less leg ulceration and priapism, but the mode of clinical presentation, prevalence of dactylitis, features of bone pain and degree of delay in sexual development, assessed by menarche, were similar in the groups. In Ugandan patients, a history of anaemic episodes was common but these were poorly documented. CONCLUSION: The haematological and clinical features of the Bantu haplotype in Uganda were broadly similar to the Benin haplotype in Jamaica except for less leg ulceration and priapism and possibly greater haemolysis among Ugandan subjects. Anaemic episodes in Uganda were treated empirically by transfusion often without a clear diagnosis; better documentation including reticulocyte counts and observations on spleen size is necessary to evolve appropriate models of care.

OBJETIVO: Comparar los rasgos clínicos de la anemia de células falciformes homocigóticas (SS) en los haplotipos Bantú y Benin en un estudio transversal de 115 pacientes ugandeses que asisten a la Clínica de la anemia de células falciformes en el Hospital de Mulago, Kampala, Uganda, con 311 pacientes en un estudio de cohorte jamaicano. MÉTODOS: El estudio conllevó la comparación de los rasgos clínicos y hematológicos con referencia especial a los determinantes genéticos de la severidad, incluyendo los niveles de la hemoglobina fetal, haplotipos del gen de la globina beta, y el estado de la alfa talasemia. RESULTADOS: El haplotipo Bantú dio cuenta del 94% de los cromosomas HbS en los pacientes ugandeses, en tanto que los haplotipos Benin dieron cuenta del 76% de los cromosomas de HbS en Jamaica. Los pacientes de Uganda presentaron una probabilidad marginalmente mayor de alfa talasemia, tenían niveles similares de hemoglobina total y hemoglobina fetal, pero en cambio presentaban conteos más altos de reticulocitos así como niveles mayores de bilirrubina total, en correspondencia con una mayor hemólisis. Los pacientes ugandeses presentaban menor ulceración de las piernas y priapismo, pero el modo de presentación clínica, la prevalencia de dactilitis, los rasgos de dolor óseo, y el grado de retraso en el desarrollo sexual, evaluado por la menarquia, fueron similares en todos los grupos. Los pacientes de Uganda se caracterizaron comúnmente por una historia de episodios de anemia, pobremente documentados. CONCLUSIÓN: Los rasgos clínicos y hematológicos del haplotipo Bantú en Uganda fueron considerablemente similares al haplotipo Benin en Jamaica, salvo por una menor presencia de ulceración de las piernas y priapismo, así como posiblemente mayor hemólisis entre los sujetos de Uganda. Los episodios de anemia en Uganda fueron tratados empíricamente mediante transfusión, a menudo sin un diagnóstico claro. Se necesita una mejor documentación - incluyendo conteos de reticulocitos - así como observaciones del tamaño del bazo, a fin de desarrollar modelos de cuidado apropiados.

Priapismo de bajo flujo convertido en priapismo de alto flujo por fístula arterio-lacunar secundaria a la técnica de Winter / Low-flow priapism developing to high-flow priapism by arterial-lacunar fistula secondary to the winter procedure

El priapismo es una afección patológica que consiste en una erección peneana persistente más allá de la estimulación sexual. Presentamos el caso de un paciente de 80 años, diagnosticado inicialmente, por la historia clínica, valores gasométricos de los cuerpos cavernosos y ultrasonografía doppler color peneana, de priapismo de bajo flujo que durante la realización de la técnica de Winter se produce iatrogénicamente la laceración bilateral de las arterias dorsales, originando una fístula arteriolacunar y en consecuencia un priapismo de alto flujo. Se realizó arteriografía selectiva de la pudenda, al no ser la eco-doppler color concluyente, que puso de manifiesto dicha fístula y permitió la embolización supraselectiva con microcoils...

Priapism is a pathology consisting of prolonged penile erection unrelated to sexual stimulation. We present an 80-year-old patient with relevant clinical history; corpora cavernosa blood gas analysis and penile Doppler ultrasound examination confirmed low-flow priapism. The Winter procedure was performed, which provoked iatrogenic laceration of the dorsal artery, leading to an arterio-lacunar fistula and high-flow priapism. A second Doppler ultrasound was inconclusive, and so a selective angiography was performed to observe the pudendal artery, following which selective embolization with microcoils was carried out...

Priapismo en pediatría: presentación inicial de una leucemia mieloide crónica / Priapism in pediatrics: initial presentation of chronic myeloid leukemia

El priapismo es una erección peneana prolongada, desencadenada o no por estímulo sexual. Es poco frecuente en pediatría, pero importa su conocimiento pues su presencia puede trasuntar enfermedades graves, como la leucemia, y también puede complicarse con la disfunción sexual eréctil irreversible, si no se establece el tratamiento oportuno. Se informa el caso de un niño de 16 años, que debuta con priapismo como presentación de una leucemia mieloide crónica. El conocimiento del cuadro de priapismo permite realizar un enfoque adecuado, aplicar de forma sistemática las exploraciones y establecer un tratamiento para prevenir sus complicaciones.

Priapism is a prolonged penis erection, triggered by sexual stimulation or not; it is uncommon in children, but its knowledge is of great importance since it may lead to suspect serious diseases, such as leukemia, and it can lead to permanent erectile dysfunction if appropriate treatment is not timely done. We present the case of a 16-year-old boy with priapism which lead to a diagnosis of chronic myeloid leukemia. Knowledge of an uncommon pathology in children, like priapism, it is very important in order to establish the suitable and timely treatment, to prevent the irreversible sequelaes and complications of this disease.

Prise en charge du priapisme chez l'enfant; au CHU de Treichville

Objectif: Le but de cette etude est d'evaluer la prise en charge du priapisme dans notre service en vue de proposer une conduite a tenir a partir d'une revue de la litterature.Patients et methodes: Il s'agit d'une etude retrospective portant sur 7 dossiers de patients suivis pour priapisme dans le service de chirurgie pediatrique du CHU de Treichville; de Janvier 2006 a Octobre 2010. Nous avons analyse: l'age; les antecedents; le delai de prise en charge; l'etiologie; les aspects cliniques; le traitement; et l'evolution.Resultats: Il s'agissait de 7 enfants de race noire; de sexe masculin; ages de 3 ans a 14 ans. Nous avons observe : un priapisme aigu chez 4 enfants (85.71) drepanocytaires SSFA2; un priapisme intermittent chez 2 enfants heterozygotes AS et 1 cas de priapisme intermittent idiopathique. Le priapisme aigu a ete traite chirurgicalement par shunt caverno-balanique unilaterale sans excision d'albuginee selon le procede de Falandry. Le priapisme intermittent a ete traite par l'administration orale d'etilefrine. Apres la chirurgie; nous avons observe 3 bons resultats immediats (75) et 1 bon resultat 24 heures apres. Aucune recidive ni aucun trouble de l'erection n'ont ete observes apres un recul moyen de 14 mois. Conclusion: Le priapisme est une complication frequente de la drepanocytose qui doit etre recherchee et traitee de facon concomitante. Nous preconisons l'injection intracaverneuse precoce d'etilefrine suivie; en cas d'echec; par la chirurgie selon la technique de Al-gorhab modifiee Falandry. Des etudes doivent etre effectuees afin d'apprecier le resultat a long terme; de cette technique; sur la fonction erectile. L'accent doit etre mis sur la sensibilisation afin de prevenir la survenue d'une impuissance sexuelle irreversible

Priapismo em crianças: revisão de fisiopatologia e tratamento: [revisão] / Priapism in children: review of pathophysiology and treatment: [review]

OBJETIVOS: O priapismo pode causar sequelas graves em relação à vida sexual futura do paciente, pois pode determinar impotência, disfunção erétil ou aversão sexual psicogênica. É um sintoma comum da doença falciforme em crianças e adolescentes. Há poucos estudos com evidências de qualidade sobre esse problema na literatura médica atual. FONTES DOS DADOS: Revisão da literatura utilizando as bases de dados MEDLINE e LILACS no período de 1966 a 2008. SÍNTESE DOS DADOS: A base para o tratamento de priapismo de baixo fluxo inclui o tratamento da doença falciforme e o uso de agentes adrenérgicos por administração intracavernosa conforme necessário. Indica-se cirurgia em uma minoria de casos. O tratamento de casos pediátricos exige ajuste de doses, escolha adequada de medicamentos e sedoanalgesia para procedimentos envolvendo dor ou trauma. CONCLUSÕES: Uma nova teoria fisiopatológica relativa à doença falciforme, que questiona os mecanismos tradicionais de bloqueio vascular por hemácias deformadas e propõe que a ativação inflamatória endotelial é a principal causa de problemas clínicos, permite propor novas manobras terapêuticas para lidar com o priapismo na doença falciforme. A ausência de evidência de qualidade para tratar o priapismo na doença falciforme sugere a necessidade de conduzir bons protocolos prospectivos multicêntricos para investigar essa condição.

OBJECTIVES: Priapism may cause serious sequelae concerning the future sex life of the patient, as it can determine impotence, erectile dysfunction or psychogenic sexual aversion. It is a common symptom of sickle cell disease in children and adolescents. There are few good quality evidence manuscripts about the problem in current medical literature. SOURCES: Literature review on the databases MEDLINE and LILACS covering the period from 1966 to 2008. SUMMARY OF THE FINDINGS: The basis for the treatment of low flow priapism includes treating sickle cell disease and the usage of intracavernous adrenergic agents as necessary. Surgery is indicated in a minority of cases. The treatment of pediatric cases demands dose adjustments, adequate drug choice and sedoanalgesia to cover procedures involving pain or trauma. CONCLUSIONS: A new physiopathologic theory concerning sickle cell disease, which questions the traditional vascular blockage mechanisms by deformed red cells and proposes that endothelial inflammatory activation is the main cause of clinical problems allows to propose new therapeutic maneuvers to solve sickle cell priapism. The absence of good quality evidence to treat sickle cell priapism suggests the necessity to conduct good prospective multicenter protocols to investigate the condition.

Penile strangulation by home-made erectile device

A 44-year-old man was admitted with penile edema and pain after having forced a narrow ring of cast iron around the base of his penis five days earlier. He was able to void without problems and there was no evidence of urinary retention. The patient, his general practitioner, and a general surgeon failed to remove the ring by various compression maneuvers. The patient was admitted to the department of urology. However, we had no instruments in our armamentarium capable of cutting cast iron. We contacted the engineering workshop of the hospital, where the engineers recommended the use of an electric iron saw. In order to protect the soft tissue from the sharp teeth of the saw a metal blade covered with a rubber sheet was passed under the iron ring. To prevent heating the saw blade was irrigated with cold water. The patient was given a muffler to protect his hearing. The ring was cut in two places and could be removed without damage to the skin. The patient was discharged the next day. One year later he reports having normal erectile function and no voiding problems

Citalopram induced priapism-the hard fact

Priapism is a persistent, usually painful, erection that lasts for more than four hours and occurs without sexual stimulation. The condition develops when blood in the penis becomes trapped and is unable to drain. This condition appears to affect only the corpora cavernosa, while the corpora spongiosum of the glans penis and surrounding urethra remain flaccid. Priapism may be a urologic emergency that is associated with the development of irreversible erectile function problems. Therefore, immediate and aggressive management may be necessary. If the condition is not treated immediately, it can lead to scarring and permanent erectile dysfunction Citalopram is a relatively new selective serotonin reuptake inhibitor [SSRI] that is becoming widely administered for the treatment of depression. Selective serotonin reuptake inhibitors generally are associated with mild adverse sexual side effects; however, more serious reactions may occur. Although selective serotonin reuptake inhibitors [SSRIs] can induce sexual side effects, such as diminished libido, delayed orgasm, anorgasmia, ejaculatory disturbances, and erectile dysfunction, priapism occurs rarely [1]. We present a case report of 45 years old gentleman who presented in A and E of Gloucester Royal Infirmary, Gloucestershire UK, with priapism of 4 days' duration

Spontaneous resolution of delayed onset, posttraumatic high-flow priapism.

Priapism is an uncommon but serious condition with major long-term sequelae. The commoner, ischemic variety is a medical emergency requiring immediate intervention in order to avoid erectile dysfunction. However,the high flow variety is non-ischemic and the patient may not seek immediate therapy. The options of management for this rare, painless form of priapism vary from conservative therapy to embolization of the internal pudendal artery or, in some cases, surgery that may result in subsequent erectile dysfunction. We present a case of a 24-year-old man who presented with priapism of six-day duration, 10 days after perineal injury. Doppler ultrasonogram of the penis revealed a cavernosal artery pseudoaneurysm. Pudendal artery angiogram done four days later revealed no leak and the priapism subsided spontaneously with subsequent return of normal erections.